precision-oncology

Precision Cancer Treatment 
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What is 
Precision Oncology?

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Precision oncology is an advanced approach to cancer care that treats tumors based on their unique genetic and molecular features, rather than their location in the body. By analyzing tumor DNA, RNA, or protein changes, clinicians can identify specific mutations that drive cancer growth and match patients to targeted therapies or immunotherapies designed to block those pathways.

With technologies like next-generation sequencing (NGS), actionable mutations can be identified across many cancers — even rare or treatment-resistant ones — enabling common treatments for cancers that behave similarly at a molecular level.

At Apollo Athenaa, genomic analysis and a multidisciplinary Tumor Board ensure each patient’s treatment plan is based on the latest evidence, precise molecular insights, and their individual health profile.

How the
Treatment Works?

At Apollo Athenaa, treatment recommendations are customized based on tumor biology, patient health, emerging evidence, and input from the Tumor Board.
precision-oncology

With precision oncology, the goal is to detect:

  • Genetic mutations (errors in DNA) (e.g., BRCA1/2, EGFR, KRAS, BRAF)
  • Gene fusions (when two genes get joined incorrectly)
  • Amplifications or deletions (too many or too few copies of the genes)
  • Microsatellite instability or tumor mutational burden (how many mutations are present in the gene)


 

Once these alterations are identified, patients may be eligible for targeted therapies that block specific molecular pathways or immunotherapies that activate the immune system. At Apollo Athenaa, these treatments are matched to the mutation rather than the tumour’s site of origin, ensuring a more precise and effective approach.

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When Precision Oncology
is Recommended?

Precision oncology — a core component of care at Apollo Athenaa — can be applied across multiple cancer types and stages, especially when more conventional treatments may be limited.
Refractory Disease

Advanced or metastatic cancers where standard treatments have stopped working or produced limited response. Precision oncology helps identify actionable mutations that may offer new, targeted therapeutic options even after multiple lines of therapy.

Rare Tumors

Cancers that are uncommon or biologically complex, often lacking standardized treatment protocols. Molecular profiling allows these tumors to be treated based on their genetic alterations, opening access to targeted therapies or clinical trials.

Unknown Primary

Cancers of unknown primary origin (CUP), where the tumor’s starting point cannot be identified. Precision oncology uses genomic signatures to guide therapy selection, enabling mutation-matched treatment despite the absence of a defined primary site.

Hereditary Risk

Patients with strong family history or hereditary cancer syndromes where inherited mutations (such as BRCA1/2, TP53, or Lynch syndrome genes) play a significant role. Genomic insights guide personalized surveillance, prevention, and targeted treatment strategies.

Key 
Advantages

Experience the benefits of advanced care tailored to your needs. At Athenaa, our approach ensures accuracy, comfort, and better outcomes at every step.
Personalization
Treatment is tailored to the tumor’s unique molecular profile, ensuring therapies directly target the genetic alterations driving cancer growth.
Improved Efficacy
Targeted therapies act on specific pathways, improving response rates while sparing healthy cells — leading to fewer and more manageable side effects.
Broader Eligibility
Precision oncology opens therapeutic avenues for rare, resistant, or previously limited-treatment cancers by focusing on mutations rather than tumor location.
Access to Emerging Therapies
Opens the door to biomarker-driven clinical trials and novel agents, providing access to next-generation treatments not available through conventional approaches.

Side Effects Of  
Precision Oncology 

At Apollo Athenaa, precision oncology treatments are designed to be more focused and less toxic, as they target specific molecular alterations driving cancer growth.Because precision oncology targets specific molecular changes, treatments tend to be more focused and less toxic than traditional chemotherapy. However, side effects can vary depending on the therapy used.
side-effects

Side effects may include:

  • Fatigue
  • Skin rash or dryness
  • Diarrhoea or gastrointestinal discomfort
  • Immune-related adverse events (with immunotherapy)


 

At Apollo Athenaa, side effect management is proactive and multidisciplinary, involving early intervention by oncologists, dermatologists, nutritionists, and nursing teams to maintain quality of life throughout treatment.

Continuum of Care

At Apollo Athenaa, precision oncology is redefining not only how cancer is treated, but also how recovery and long-term wellbeing are supported — making every woman’s journey more informed, targeted, and hopeful.
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Ongoing surveillance imaging and lab tests

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Monitoring for recurrence or resistance mutations

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Assessment for new therapy eligibility if disease evolves

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Survivorship planning, addressing long-term side effects, psychosocial support, and quality of life

Frequently Asked Questions

Do I need to request genomic testing, or will my doctor tell me if I need it?
01

At Apollo Athenaa, your oncologist evaluates your case and recommends genomic testing when it can meaningfully guide treatment — especially for rare, advanced, or treatment-resistant cancers.

If my cancer has a mutation, does that mean my family is at risk too?
02

Not always. Many mutations are acquired by tumor cells and not inherited. At Apollo Athenaa, genetic counsellors help determine whether your mutation has hereditary implications for your daughters, siblings, or other family members.

Will precision oncology delay the start of my treatment?
03

Testing can take a few days to a few weeks depending on the complexity. At Apollo Athenaa, your doctors may begin supportive or bridging treatment if required, and final therapy decisions are made as soon as results arrive.

What happens if my tumor has no actionable mutations?
04

Not all tumours carry targetable mutations. If that happens, Apollo Athenaa’s oncology team discusses alternative treatments such as immunotherapy, chemotherapy, or clinical trials, ensuring you still have a clear and evidence-based plan.

Is precision oncology safe?
05

Yes. It often leads to fewer side effects because it targets only cancer-specific pathways. Apollo Athenaa ensures continuous monitoring, early intervention, and supportive care to maximize safety and comfort.

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